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This course is approved by the Royal Society of Biology with 9 CPD credits
The Immune System can display paradoxical activity as both ally and rival in the Carcinogenic process. In Subject 05, we delve into the molecular mechanisms involved, specifically that of Membrane Receptor interactions and secretion of Cytokines. You will also learn about how the Immune System cells, such as Macrophages, Dendritic Cells, Cytotoxic T lymphocytes and NK Cells, fight against tumor cells in the initial stages of cancer, as well as how when Tumor Immunosuppression arises in the more advanced stages, some immune cells such as TAMs and MDSCs become allies of the tumor cells.
What will you learn?
With this course you
will learn about:
Anti-cancer immune response.
Innate and adaptive immune system.
Antigen processing and presentation.
Immune cells role in cancer: Macrophages, Neutrophils, Dendritic cells, Natural killer cells (NK cells), Natural Killer T cells and T lymphocytes.
Cytokines involve in anti-cancer immune response: interleukins 1 alpha and beta (il1A and IL1B), interleukin 6 (IL-6), chemokines 9 and 10 (CXCL9 and CXCL10), and tumor necrosis factor alpha (TNFA).
JAK/STAT signaling pathway, tumor immunoediting and immunosupression of the cytotoxic response.